Cargando…

High level expression of the anti-retroviral protein APOBEC3G is induced by influenza A virus but does not confer antiviral activity

Human APOBEC3G is an antiretroviral protein that was described to act via deamination of retroviral cDNA. However, it was suggested that APOBEC proteins might act with antiviral activity by yet other mechanisms and may also possess RNA deamination activity. As a consequence there is an ongoing debat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pauli, Eva-K, Schmolke, Mirco, Hofmann, Henning, Ehrhardt, Christina, Flory, Egbert, Münk, Carsten, Ludwig, Stephan
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672920/ https://www.ncbi.nlm.nih.gov/pubmed/19371434 http://dx.doi.org/10.1186/1742-4690-6-38

Ejemplares similares

Sp1 and Sp3 regulate basal transcription of the human APOBEC3G gene
por: Muckenfuss, Heide, et al.
Publicado: (2007)

Influenza A Virus Inhibits Type I IFN Signaling via NF-κB-Dependent Induction of SOCS-3 Expression
por: Pauli, Eva-K., et al.
Publicado: (2008)

Human LINE-1 restriction by APOBEC3C is deaminase independent and mediated by an ORF1p interaction that affects LINE reverse transcriptase activity
por: Horn, Axel V., et al.
Publicado: (2014)

APOBEC4 Enhances the Replication of HIV-1
por: Marino, Daniela, et al.
Publicado: (2016)

Targeting APOBEC3A to the viral nucleoprotein complex confers antiviral activity
por: Goila-Gaur, Ritu, et al.
Publicado: (2007)

Human Retroviral Host Restriction Factors APOBEC3G and APOBEC3F Localize to mRNA Processing Bodies
por: Wichroski, Michael J, et al.
Publicado: (2006)

Foamy Viruses, Bet, and APOBEC3 Restriction
por: Jaguva Vasudevan, Ananda Ayyappan, et al.
Publicado: (2021)

Inhibition of p38 Mitogen-activated Protein Kinase Impairs Influenza Virus-induced Primary and Secondary Host Gene Responses and Protects Mice from Lethal H5N1 Infection
por: Börgeling, Yvonne, et al.
Publicado: (2014)

Proteinase-Activated Receptor-2 Agonist Activates Anti-Influenza Mechanisms and Modulates IFNγ-Induced Antiviral Pathways in Human Neutrophils
por: Feld, Micha, et al.
Publicado: (2013)

Antiviral activity of Ladania067, an extract from wild black currant leaves against influenza A virus in vitro and in vivo
por: Haasbach, Emanuel, et al.
Publicado: (2014)

An ancient history of gene duplications, fusions and losses in the evolution of APOBEC3 mutators in mammals
por: Münk, Carsten, et al.
Publicado: (2012)

Vaccinia virus replication is not affected by APOBEC3 family members
por: Kremer, Melanie, et al.
Publicado: (2006)

A Naturally Occurring Domestic Cat APOBEC3 Variant Confers Resistance to Feline Immunodeficiency Virus Infection
por: Yoshikawa, Rokusuke, et al.
Publicado: (2015)

Feline APOBEC3s, Barriers to Cross-Species Transmission of FIV?
por: Zhang, Zeli, et al.
Publicado: (2018)

Multi-Scale Modeling of HIV Infection in vitro and APOBEC3G-Based Anti-Retroviral Therapy
por: Hosseini, Iraj, et al.
Publicado: (2012)

Phosphoproteomic-based kinase profiling early in influenza virus infection identifies GRK2 as antiviral drug target
por: Yángüez, Emilio, et al.
Publicado: (2018)

Antiviral Mechanism and Biochemical Basis of the Human APOBEC3 Family
por: Imahashi, Mayumi, et al.
Publicado: (2012)

Mutagenic Activity of AID/APOBEC Deaminases in Antiviral Defense and Carcinogenesis
por: Shilova, O. N., et al.
Publicado: (2022)

Pharmacodynamics, Pharmacokinetics, and Antiviral Activity of BAY 81-8781, a Novel NF-κB Inhibiting Anti-influenza Drug
por: Droebner, Karoline, et al.
Publicado: (2017)

Retroviral Restriction Factor APOBEC3G Delays the Initiation of DNA Synthesis by HIV-1 Reverse Transcriptase
por: Adolph, Madison B., et al.
Publicado: (2013)

Targeting intracellular signaling as an antiviral strategy: aerosolized LASAG for the treatment of influenza in hospitalized patients
por: Scheuch, Gerhard, et al.
Publicado: (2018)

Evidence for a Novel Mechanism of Influenza Virus-Induced Type I Interferon Expression by a Defective RNA-Encoded Protein
por: Boergeling, Yvonne, et al.
Publicado: (2015)

Mutational comparison of the single-domained APOBEC3C and double-domained APOBEC3F/G anti-retroviral cytidine deaminases provides insight into their DNA target site specificities
por: Langlois, Marc-André, et al.
Publicado: (2005)

Influenza A viruses suppress cyclooxygenase-2 expression by affecting its mRNA stability
por: Dudek, Sabine Eva, et al.
Publicado: (2016)

Structural Features of Antiviral APOBEC3 Proteins are Linked to Their Functional Activities
por: Kitamura, Shingo, et al.
Publicado: (2011)

Structure of the Vif-binding domain of the antiviral enzyme APOBEC3G
por: Kouno, Takahide, et al.
Publicado: (2015)

Retrocopying expands the functional repertoire of APOBEC3 antiviral proteins in primates
por: Yang, Lei, et al.
Publicado: (2020)

Vemurafenib Limits Influenza A Virus Propagation by Targeting Multiple Signaling Pathways
por: Holzberg, Magdalena, et al.
Publicado: (2017)

Identification of the feline foamy virus Bet domain essential for APOBEC3 counteraction
por: Lukic, Dragana Slavkovic, et al.
Publicado: (2013)

Influenza A virus infection impacts systemic microbiota dynamics and causes quantitative enteric dysbiosis
por: Yildiz, Soner, et al.
Publicado: (2018)

The influenza replication blocking inhibitor LASAG does not sensitize human epithelial cells for bacterial infections
por: Wilden, Janine J., et al.
Publicado: (2020)

Adaptive Evolution of Mus Apobec3 Includes Retroviral Insertion and Positive Selection at Two Clusters of Residues Flanking the Substrate Groove
por: Sanville, Bradley, et al.
Publicado: (2010)

Mouse APOBEC3 affects the production of virus-neutralizing antibodies by restricting early retroviral replication, not by altering the B-cell repertoire
por: Miyazawa, Masaaki, et al.
Publicado: (2009)

Polymorphisms in Human APOBEC3H Differentially Regulate Ubiquitination and Antiviral Activity
por: Chesarino, Nicholas M., et al.
Publicado: (2020)

The Epidermal Growth Factor Receptor (EGFR) Promotes Uptake of Influenza A Viruses (IAV) into Host Cells
por: Eierhoff, Thorsten, et al.
Publicado: (2010)

Altered Signal Transduction in the Immune Response to Influenza Virus and S. pneumoniae or S. aureus Co-Infections
por: Wilden, Janine J., et al.
Publicado: (2021)

Dose of Retroviral Infection Determines Induction of Antiviral NK Cell Responses
por: Littwitz-Salomon, Elisabeth, et al.
Publicado: (2017)

Running Loose or Getting Lost: How HIV-1 Counters and Capitalizes on APOBEC3-Induced Mutagenesis through Its Vif Protein
por: Münk, Carsten, et al.
Publicado: (2012)

Functions, structure, and read-through alternative splicing of feline APOBEC3 genes
por: Münk, Carsten, et al.
Publicado: (2008)

Ancient Adaptive Evolution of the Primate Antiviral DNA-Editing Enzyme APOBEC3G
por: Sawyer, Sara L, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_i9pjh9det96lsmm9m592r7v9sl