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LRP1 shedding in human brain: roles of ADAM10 and ADAM17

BACKGROUND: The low-density lipoprotein receptor-related protein 1 (LRP1) plays critical roles in lipid metabolism, cell survival, and the clearance of amyloid-β (Aβ) peptide. Functional soluble LRP1 (sLRP1) has been detected in circulating human placenta; however, whether sLRP1 is also present in t...

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Detalles Bibliográficos
Autores principales:	Liu, Qiang, Zhang, Juan, Tran, Hien, Verbeek, Marcel M, Reiss, Karina, Estus, Steven, Bu, Guojun
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672942/ https://www.ncbi.nlm.nih.gov/pubmed/19371428 http://dx.doi.org/10.1186/1750-1326-4-17

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