Comparison of T Cell Receptor-Induced Proximal Signaling and Downstream Functions in Immortalized and Primary T Cells

BACKGROUND: Human T cells play an important role in pathogen clearance, but their aberrant activation is also linked to numerous diseases. T cells are activated by the concurrent induction of the T cell receptor (TCR) and one or more costimulatory receptors. The characterization of signaling pathway...

Descripción completa

Detalles Bibliográficos
Autores principales: Bartelt, Rebekah R., Cruz-Orcutt, Noemi, Collins, Michaela, Houtman, Jon C. D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673025/
https://www.ncbi.nlm.nih.gov/pubmed/19412549
http://dx.doi.org/10.1371/journal.pone.0005430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673025/
https://www.ncbi.nlm.nih.gov/pubmed/19412549
http://dx.doi.org/10.1371/journal.pone.0005430

Ejemplares similares