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Comparison of T Cell Receptor-Induced Proximal Signaling and Downstream Functions in Immortalized and Primary T Cells

BACKGROUND: Human T cells play an important role in pathogen clearance, but their aberrant activation is also linked to numerous diseases. T cells are activated by the concurrent induction of the T cell receptor (TCR) and one or more costimulatory receptors. The characterization of signaling pathway...

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Detalles Bibliográficos
Autores principales:	Bartelt, Rebekah R., Cruz-Orcutt, Noemi, Collins, Michaela, Houtman, Jon C. D.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673025/ https://www.ncbi.nlm.nih.gov/pubmed/19412549 http://dx.doi.org/10.1371/journal.pone.0005430

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