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Safety Implications of High-Field MRI: Actuation of Endogenous Magnetic Iron Oxides in the Human Body

BACKGROUND: Magnetic Resonance Imaging scanners have become ubiquitous in hospitals and high-field systems (greater than 3 Tesla) are becoming increasingly common. In light of recent European Union moves to limit high-field exposure for those working with MRI scanners, we have evaluated the potentia...

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Detalles Bibliográficos
Autores principales: Dobson, Jon, Bowtell, Richard, Garcia-Prieto, Ana, Pankhurst, Quentin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673027/
https://www.ncbi.nlm.nih.gov/pubmed/19412550
http://dx.doi.org/10.1371/journal.pone.0005431
Descripción
Sumario:BACKGROUND: Magnetic Resonance Imaging scanners have become ubiquitous in hospitals and high-field systems (greater than 3 Tesla) are becoming increasingly common. In light of recent European Union moves to limit high-field exposure for those working with MRI scanners, we have evaluated the potential for detrimental cellular effects via nanomagnetic actuation of endogenous iron oxides in the body. METHODOLOGY: Theoretical models and experimental data on the composition and magnetic properties of endogenous iron oxides in human tissue were used to analyze the forces on iron oxide particles. PRINCIPAL FINDING AND CONCLUSIONS: Results show that, even at 9.4 Tesla, forces on these particles are unlikely to disrupt normal cellular function via nanomagnetic actuation.