Safety Implications of High-Field MRI: Actuation of Endogenous Magnetic Iron Oxides in the Human Body

BACKGROUND: Magnetic Resonance Imaging scanners have become ubiquitous in hospitals and high-field systems (greater than 3 Tesla) are becoming increasingly common. In light of recent European Union moves to limit high-field exposure for those working with MRI scanners, we have evaluated the potentia...

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Detalles Bibliográficos
Autores principales: Dobson, Jon, Bowtell, Richard, Garcia-Prieto, Ana, Pankhurst, Quentin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673027/
https://www.ncbi.nlm.nih.gov/pubmed/19412550
http://dx.doi.org/10.1371/journal.pone.0005431
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author Dobson, Jon
Bowtell, Richard
Garcia-Prieto, Ana
Pankhurst, Quentin
author_facet Dobson, Jon
Bowtell, Richard
Garcia-Prieto, Ana
Pankhurst, Quentin
author_sort Dobson, Jon
collection PubMed
description BACKGROUND: Magnetic Resonance Imaging scanners have become ubiquitous in hospitals and high-field systems (greater than 3 Tesla) are becoming increasingly common. In light of recent European Union moves to limit high-field exposure for those working with MRI scanners, we have evaluated the potential for detrimental cellular effects via nanomagnetic actuation of endogenous iron oxides in the body. METHODOLOGY: Theoretical models and experimental data on the composition and magnetic properties of endogenous iron oxides in human tissue were used to analyze the forces on iron oxide particles. PRINCIPAL FINDING AND CONCLUSIONS: Results show that, even at 9.4 Tesla, forces on these particles are unlikely to disrupt normal cellular function via nanomagnetic actuation.
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spelling pubmed-26730272009-05-04 Safety Implications of High-Field MRI: Actuation of Endogenous Magnetic Iron Oxides in the Human Body Dobson, Jon Bowtell, Richard Garcia-Prieto, Ana Pankhurst, Quentin PLoS One Research Article BACKGROUND: Magnetic Resonance Imaging scanners have become ubiquitous in hospitals and high-field systems (greater than 3 Tesla) are becoming increasingly common. In light of recent European Union moves to limit high-field exposure for those working with MRI scanners, we have evaluated the potential for detrimental cellular effects via nanomagnetic actuation of endogenous iron oxides in the body. METHODOLOGY: Theoretical models and experimental data on the composition and magnetic properties of endogenous iron oxides in human tissue were used to analyze the forces on iron oxide particles. PRINCIPAL FINDING AND CONCLUSIONS: Results show that, even at 9.4 Tesla, forces on these particles are unlikely to disrupt normal cellular function via nanomagnetic actuation. Public Library of Science 2009-05-04 /pmc/articles/PMC2673027/ /pubmed/19412550 http://dx.doi.org/10.1371/journal.pone.0005431 Text en Dobson et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Dobson, Jon
Bowtell, Richard
Garcia-Prieto, Ana
Pankhurst, Quentin
Safety Implications of High-Field MRI: Actuation of Endogenous Magnetic Iron Oxides in the Human Body
title Safety Implications of High-Field MRI: Actuation of Endogenous Magnetic Iron Oxides in the Human Body
title_full Safety Implications of High-Field MRI: Actuation of Endogenous Magnetic Iron Oxides in the Human Body
title_fullStr Safety Implications of High-Field MRI: Actuation of Endogenous Magnetic Iron Oxides in the Human Body
title_full_unstemmed Safety Implications of High-Field MRI: Actuation of Endogenous Magnetic Iron Oxides in the Human Body
title_short Safety Implications of High-Field MRI: Actuation of Endogenous Magnetic Iron Oxides in the Human Body
title_sort safety implications of high-field mri: actuation of endogenous magnetic iron oxides in the human body
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673027/
https://www.ncbi.nlm.nih.gov/pubmed/19412550
http://dx.doi.org/10.1371/journal.pone.0005431
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