Ancient mtDNA Genetic Variants Modulate mtDNA Transcription and Replication

Although the functional consequences of mitochondrial DNA (mtDNA) genetic backgrounds (haplotypes, haplogroups) have been demonstrated by both disease association studies and cell culture experiments, it is not clear which of the mutations within the haplogroup carry functional implications and whic...

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Detalles Bibliográficos
Autores principales: Suissa, Sarit, Wang, Zhibo, Poole, Jason, Wittkopp, Sharine, Feder, Jeanette, Shutt, Timothy E., Wallace, Douglas C., Shadel, Gerald S., Mishmar, Dan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673036/
https://www.ncbi.nlm.nih.gov/pubmed/19424428
http://dx.doi.org/10.1371/journal.pgen.1000474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673036/
https://www.ncbi.nlm.nih.gov/pubmed/19424428
http://dx.doi.org/10.1371/journal.pgen.1000474

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