The Eukaryotic Ribosome: Current Status and Challenges

Despite having been identified first, their greater degree of complexity has resulted in our understanding of eukaryotic ribosomes lagging behind that of their bacterial and archaeal counterparts. A much more complicated biogenesis program results in ribosomes that are structurally, biochemically, a...

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Detalles Bibliográficos
Autor principal: Dinman, Jonathan D.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Minireviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673243/
https://www.ncbi.nlm.nih.gov/pubmed/19117941
http://dx.doi.org/10.1074/jbc.R800074200
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author Dinman, Jonathan D.
author_facet Dinman, Jonathan D.
author_sort Dinman, Jonathan D.
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description Despite having been identified first, their greater degree of complexity has resulted in our understanding of eukaryotic ribosomes lagging behind that of their bacterial and archaeal counterparts. A much more complicated biogenesis program results in ribosomes that are structurally, biochemically, and functionally more complex. However, recent advances in molecular genetics and structural biology are helping to reveal the intricacies of the eukaryotic ribosome and to address many longstanding questions regarding its many roles in the regulation of gene expression.
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spelling pubmed-26732432009-05-05 The Eukaryotic Ribosome: Current Status and Challenges Dinman, Jonathan D. J Biol Chem Minireviews Despite having been identified first, their greater degree of complexity has resulted in our understanding of eukaryotic ribosomes lagging behind that of their bacterial and archaeal counterparts. A much more complicated biogenesis program results in ribosomes that are structurally, biochemically, and functionally more complex. However, recent advances in molecular genetics and structural biology are helping to reveal the intricacies of the eukaryotic ribosome and to address many longstanding questions regarding its many roles in the regulation of gene expression. American Society for Biochemistry and Molecular Biology 2009-05-01 /pmc/articles/PMC2673243/ /pubmed/19117941 http://dx.doi.org/10.1074/jbc.R800074200 Text en Copyright © 2009, The American Society for Biochemistry and Molecular Biology, Inc. Author's Choice Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) applies to Author Choice Articles
spellingShingle Minireviews
Dinman, Jonathan D.
The Eukaryotic Ribosome: Current Status and Challenges
title The Eukaryotic Ribosome: Current Status and Challenges
title_full The Eukaryotic Ribosome: Current Status and Challenges
title_fullStr The Eukaryotic Ribosome: Current Status and Challenges
title_full_unstemmed The Eukaryotic Ribosome: Current Status and Challenges
title_short The Eukaryotic Ribosome: Current Status and Challenges
title_sort eukaryotic ribosome: current status and challenges
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673243/
https://www.ncbi.nlm.nih.gov/pubmed/19117941
http://dx.doi.org/10.1074/jbc.R800074200
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