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The human GINS complex associates with Cdc45 and MCM and is essential for DNA replication

The GINS complex, originally discovered in Saccharomyces cerevisiae and Xenopus laevis, binds to DNA replication origins shortly before the onset of S phase and travels with the replication forks after initiation. In this study we present a detailed characterization of the human GINS (hGINS) homolog...

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Detalles Bibliográficos
Autores principales:	Aparicio, Tomás, Guillou, Emmanuelle, Coloma, Javier, Montoya, Guillermo, Méndez, Juan
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673421/ https://www.ncbi.nlm.nih.gov/pubmed/19223333 http://dx.doi.org/10.1093/nar/gkp065

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