A short motif in Drosophila SECIS Binding Protein 2 provides differential binding affinity to SECIS RNA hairpins

Selenoproteins contain the amino acid selenocysteine which is encoded by a UGA Sec codon. Recoding UGA Sec requires a complex mechanism, comprising the cis-acting SECIS RNA hairpin in the 3′UTR of selenoprotein mRNAs, and trans-acting factors. Among these, the SECIS Binding Protein 2 (SBP2) is centr...

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Detalles Bibliográficos
Autores principales: Takeuchi, Akiko, Schmitt, David, Chapple, Charles, Babaylova, Elena, Karpova, Galina, Guigo, Roderic, Krol, Alain, Allmang, Christine
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673426/
https://www.ncbi.nlm.nih.gov/pubmed/19223320
http://dx.doi.org/10.1093/nar/gkp078

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