Replication initiation complex formation in the absence of nuclear function in Xenopus

In this article, we study how intercalation-induced changes in chromatin and DNA topology affect chromosomal DNA replication using Xenopus egg extracts. Unexpectedly, intercalation by ethidium or doxorubicin prevents formation of a functional nucleus: although nucleosome formation occurs, DNA decond...

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Detalles Bibliográficos
Autores principales: Krasinska, Liliana, Fisher, Daniel
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673427/
https://www.ncbi.nlm.nih.gov/pubmed/19237397
http://dx.doi.org/10.1093/nar/gkp081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673427/
https://www.ncbi.nlm.nih.gov/pubmed/19237397
http://dx.doi.org/10.1093/nar/gkp081

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