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Mutational analysis of a Dcp2-binding element reveals general enhancement of decapping by 5′-end stem-loop structures
mRNA decapping is a critical step in the control of mRNA stability and gene expression and is carried out by the Dcp2 protein. Dcp2 is an RNA-binding protein that must bind the RNA in order to recognize the cap for hydrolysis. We previously demonstrated that a 60 nucleotide (nt) element at the 5′ en...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673433/ https://www.ncbi.nlm.nih.gov/pubmed/19233875 http://dx.doi.org/10.1093/nar/gkp087 |