Species-Specific Activity of SIV Nef and HIV-1 Vpu in Overcoming Restriction by Tetherin/BST2

Tetherin, also known as BST2, CD317 or HM1.24, was recently identified as an interferon-inducible host–cell factor that interferes with the detachment of virus particles from infected cells. HIV-1 overcomes this restriction by expressing an accessory protein, Vpu, which counteracts tetherin. Since l...

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Detalles Bibliográficos
Autores principales: Jia, Bin, Serra-Moreno, Ruth, Neidermyer, William, Rahmberg, Andrew, Mackey, John, Fofana, Ismael Ben, Johnson, Welkin E., Westmoreland, Susan, Evans, David T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673686/
https://www.ncbi.nlm.nih.gov/pubmed/19436700
http://dx.doi.org/10.1371/journal.ppat.1000429

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