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Avian Influenza Virus Glycoproteins Restrict Virus Replication and Spread through Human Airway Epithelium at Temperatures of the Proximal Airways

Transmission of avian influenza viruses from bird to human is a rare event even though avian influenza viruses infect the ciliated epithelium of human airways in vitro and ex vivo. Using an in vitro model of human ciliated airway epithelium (HAE), we demonstrate that while human and avian influenza...

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Detalles Bibliográficos
Autores principales: Scull, Margaret A., Gillim-Ross, Laura, Santos, Celia, Roberts, Kim L., Bordonali, Elena, Subbarao, Kanta, Barclay, Wendy S., Pickles, Raymond J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673688/
https://www.ncbi.nlm.nih.gov/pubmed/19436701
http://dx.doi.org/10.1371/journal.ppat.1000424