Cargando…
Avian Influenza Virus Glycoproteins Restrict Virus Replication and Spread through Human Airway Epithelium at Temperatures of the Proximal Airways
Transmission of avian influenza viruses from bird to human is a rare event even though avian influenza viruses infect the ciliated epithelium of human airways in vitro and ex vivo. Using an in vitro model of human ciliated airway epithelium (HAE), we demonstrate that while human and avian influenza...
Autores principales: | Scull, Margaret A., Gillim-Ross, Laura, Santos, Celia, Roberts, Kim L., Bordonali, Elena, Subbarao, Kanta, Barclay, Wendy S., Pickles, Raymond J. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673688/ https://www.ncbi.nlm.nih.gov/pubmed/19436701 http://dx.doi.org/10.1371/journal.ppat.1000424 |
Ejemplares similares
-
Can Immunity Induced by the Human Influenza Virus N1 Neuraminidase Provide Some Protection from Avian Influenza H5N1 Viruses?
por: Gillim-Ross, Laura, et al.
Publicado: (2007) -
Mutations in H5N1 Influenza Virus Hemagglutinin that Confer Binding to Human Tracheal Airway Epithelium
por: Ayora-Talavera, Guadalupe, et al.
Publicado: (2009) -
Growth restriction of an experimental live attenuated human parainfluenza virus type 2 vaccine in human ciliated airway epithelium in vitro parallels attenuation in African green monkeys
por: Schaap-Nutt, Anne, et al.
Publicado: (2010) -
Influenza Virus with Increased pH of Hemagglutinin Activation Has Improved Replication in Cell Culture but at the Cost of Infectivity in Human Airway Epithelium
por: Singanayagam, Anika, et al.
Publicado: (2019) -
Scientific barriers to developing vaccines against avian influenza viruses
por: Subbarao, Kanta, et al.
Publicado: (2007)