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RGD targeted poly(L-glutamic acid)-cystamine-(Gd-DO3A) conjugate for detecting angiogenesis biomarker α(ν)β(3) integrin with MR T(1) mapping
Cyclic Arg-Gly-Asp-D-Phe-Lys [c(RGDfK)] targeted poly(L-glutamic acid) (PGA)-(Gd-DO3A) conjugate with a biodegradable cystamine spacer was prepared and evaluated for in vivo detection of an angiogenesis biomarker, α(ν)β(3) integrin, in neoplastic tissues with T(1) mapping, a quantitative magnetic re...
Autores principales: | Ke, Tianyi, Jeong, Eun-Kee, Wang, Xuli, Feng, Yi, Parker, Dennis L, Lu, Zheng-Rong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673968/ https://www.ncbi.nlm.nih.gov/pubmed/17722547 |
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