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Natural genetic variation in transcriptome reflects network structure inferred with major effect mutations: insulin/TOR and associated phenotypes in Drosophila melanogaster
BACKGROUND: A molecular process based genotype-to-phenotype map will ultimately enable us to predict how genetic variation among individuals results in phenotypic alterations. Building such a map is, however, far from straightforward. It requires understanding how molecular variation re-shapes devel...
Autores principales: | Nuzhdin, Sergey V, Brisson, Jennifer A, Pickering, Andrew, Wayne, Marta L, Harshman, Lawrence G, McIntyre, Lauren M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674066/ https://www.ncbi.nlm.nih.gov/pubmed/19317915 http://dx.doi.org/10.1186/1471-2164-10-124 |
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