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Generation, Characterization and Epitope Mapping of Two Neutralizing and Protective Human Recombinant Antibodies against Influenza A H5N1 Viruses

BACKGROUND: The development of new therapeutic targets and strategies to control highly pathogenic avian influenza (HPAI) H5N1 virus infection in humans is urgently needed. Broadly cross-neutralizing recombinant human antibodies obtained from the survivors of H5N1 avian influenza provide an importan...

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Detalles Bibliográficos
Autores principales: Sun, Lina, Lu, Xiuhua, Li, Chuan, Wang, Min, Liu, Qinzhi, Li, Zi, Hu, Xiaofen, Li, Jiandong, Liu, Feng, Li, Qun, Belser, Jessica A., Hancock, Kathy, Shu, Yuelong, Katz, Jacqueline M., Liang, Mifang, Li, Dexin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674214/
https://www.ncbi.nlm.nih.gov/pubmed/19421326
http://dx.doi.org/10.1371/journal.pone.0005476