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Array-Based Approaches for the Identification of Epigenetic Silenced Tumor Suppressor Genes
Carcinogenesis involves the inactivation or inhibition of genes that function as tumor suppressors. Deletions, mutations, or epigenetic silencing of tumor suppressor genes can lead to altered growth, differentiation, and apoptosis. DNA methylation and histone modifications are important epigenetic m...
Autores principales: | Takai, Noriyuki, Narahara, Hisashi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers Ltd.
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674306/ https://www.ncbi.nlm.nih.gov/pubmed/19424480 http://dx.doi.org/10.2174/138920208783884892 |
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