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Correlated evolution of nucleotide substitution rates and allelic variation in Mhc-DRB lineages of primates

BACKGROUND: The major histocompatibility complex (MHC) is a key model of genetic polymorphism. Selection pressure by pathogens or other microevolutionary forces may result in a high rate of non-synonymous substitutions at the codons specifying the contact residues of the antigen binding sites (ABS),...

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Detalles Bibliográficos
Autores principales:	Garamszegi, László Z, de Groot, Natasja G, Bontrop, Ronald E
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674423/ https://www.ncbi.nlm.nih.gov/pubmed/19361342 http://dx.doi.org/10.1186/1471-2148-9-73

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