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The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis
BACKGROUND: Histone methylation is thought to be central to the epigenetic mechanisms that maintain and confine cellular identity in multi-cellular organisms. To examine epigenetic roles in cellular homeostasis, we conditionally mutated the histone 3 lysine 4 methyltransferase, Mll2, in embryonic st...
Autores principales: | Glaser, Stefan, Lubitz, Sandra, Loveland, Kate L, Ohbo, Kazu, Robb, Lorraine, Schwenk, Frieder, Seibler, Jost, Roellig, Daniela, Kranz, Andrea, Anastassiadis, Konstantinos, Stewart, A Francis |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674429/ https://www.ncbi.nlm.nih.gov/pubmed/19348672 http://dx.doi.org/10.1186/1756-8935-2-5 |
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