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Mixed allele malaria vaccines: Host protection and within-host selection
Malaria parasites are frequently polymorphic at the antigenic targets of many candidate vaccines, presumably as a consequence of selection pressure from protective immune responses. Conventional wisdom is therefore that vaccines directed against a single variant could select for non-target variants,...
Autores principales: | Barclay, Victoria C., Chan, Brian H.K., Anders, Robin F., Read, Andrew F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674600/ https://www.ncbi.nlm.nih.gov/pubmed/18804509 http://dx.doi.org/10.1016/j.vaccine.2008.09.004 |
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