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Enhanced release of IgE-dependent early phase mediators from nasal polyp tissue

BACKGROUND: The mast cell is a crucial effector cell in allergic rhinitis and other inflammatory diseases. During the acute allergic reaction preformed mediators such as histamine, but also de novo produced mediators such as leukotrienes (LTC(4)/D(4)/E(4)) and prostaglandins (PGD(2)) are released. M...

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Detalles Bibliográficos
Autores principales: Patou, Joke, Holtappels, Gabriele, Affleck, Karen, Gevaert, Philippe, Perez-Novo, Claudina, Van Cauwenberge, Paul, Bachert, Claus
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674877/
https://www.ncbi.nlm.nih.gov/pubmed/19379488
http://dx.doi.org/10.1186/1476-9255-6-11