MAVS-Mediated Apoptosis and Its Inhibition by Viral Proteins

BACKGROUND: Host responses to viral infection include both immune activation and programmed cell death. The mitochondrial antiviral signaling adaptor, MAVS (IPS-1, VISA or Cardif) is critical for host defenses to viral infection by inducing type-1 interferons (IFN-I), however its role in virus-induc...

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Detalles Bibliográficos
Autores principales: Lei, Yu, Moore, Chris B., Liesman, Rachael M., O'Connor, Brian P., Bergstralh, Daniel T., Chen, Zhijian J., Pickles, Raymond J., Ting, Jenny P.-Y.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674933/
https://www.ncbi.nlm.nih.gov/pubmed/19404494
http://dx.doi.org/10.1371/journal.pone.0005466

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