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CHOP Mediates Endoplasmic Reticulum Stress-Induced Apoptosis in Gimap5-Deficient T Cells
Gimap5 (GTPase of the immunity-associated protein 5) has been linked to the regulation of T cell survival, and polymorphisms in the human GIMAP5 gene associate with autoimmune disorders. The BioBreeding diabetes-prone (BBDP) rat has a mutation in the Gimap5 gene that leads to spontaneous apoptosis o...
Autores principales: | Pino, Steven C., O'Sullivan-Murphy, Bryan, Lidstone, Erich A., Yang, Chaoxing, Lipson, Kathryn L., Jurczyk, Agata, diIorio, Philip, Brehm, Michael A., Mordes, John P., Greiner, Dale L., Rossini, Aldo A., Bortell, Rita |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674944/ https://www.ncbi.nlm.nih.gov/pubmed/19424493 http://dx.doi.org/10.1371/journal.pone.0005468 |
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