Structural and Functional Dissection of the Heterocyclic Peptide Cytotoxin Streptolysin S

The human pathogen Streptococcus pyogenes secretes a highly cytolytic toxin known as streptolysin S (SLS). SLS is a key virulence determinant and responsible for the β-hemolytic phenotype of these bacteria. Despite over a century of research, the chemical structure of SLS remains unknown. Recent exp...

Descripción completa

Detalles Bibliográficos
Autores principales: Mitchell, Douglas A., Lee, Shaun W., Pence, Morgan A., Markley, Andrew L., Limm, Joyce D., Nizet, Victor, Dixon, Jack E.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Protein Synthesis, Post-Translational Modification, and Degradation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676033/
https://www.ncbi.nlm.nih.gov/pubmed/19286651
http://dx.doi.org/10.1074/jbc.M900802200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676033/
https://www.ncbi.nlm.nih.gov/pubmed/19286651
http://dx.doi.org/10.1074/jbc.M900802200

Ejemplares similares