Wound Healing Effects of Arnebia Densiflora Root Extracts on Rat Palatal Mucosa

OBJECTIVES: The aim of this study was to investigate wound healing effects of Arnebia densiflora (Nordm.) Ledeb. root extracts on rat palatal mucosa. METHODS: A 10-mm full-thickness mucosal wounds were created on midline of rats’ palate by using scalpel. In the experimental groups, a ten percent ext...

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Detalles Bibliográficos
Autores principales: Kosger, H. Huseyin, Ozturk, Mustafa, Sokmen, Atalay, Bulut, Eray, Ay, Sinan
Formato: Texto
Lenguaje:English
Publicado: Dental Investigations Society 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676067/
https://www.ncbi.nlm.nih.gov/pubmed/19421388
Descripción
Sumario:OBJECTIVES: The aim of this study was to investigate wound healing effects of Arnebia densiflora (Nordm.) Ledeb. root extracts on rat palatal mucosa. METHODS: A 10-mm full-thickness mucosal wounds were created on midline of rats’ palate by using scalpel. In the experimental groups, a ten percent extract of A. densiflora roots was topically applied once a day as ointment on the wounds. After wounding, tissue samples from palatal mucosa were harvested at 4, 7, 14 and 21 days and then evaluated histologically. RESULTS: It was observed that 10% A. densiflora root extract has progressive effects on wound healing in experimental groups. CONCLUSIONS: This study suggests that A. densiflora root extract could be developed as a therapeutic agent for wound healing.

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