Wound Healing Effects of Arnebia Densiflora Root Extracts on Rat Palatal Mucosa

OBJECTIVES: The aim of this study was to investigate wound healing effects of Arnebia densiflora (Nordm.) Ledeb. root extracts on rat palatal mucosa. METHODS: A 10-mm full-thickness mucosal wounds were created on midline of rats’ palate by using scalpel. In the experimental groups, a ten percent ext...

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Autores principales: Kosger, H. Huseyin, Ozturk, Mustafa, Sokmen, Atalay, Bulut, Eray, Ay, Sinan
Formato: Texto
Lenguaje:English
Publicado: Dental Investigations Society 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676067/
https://www.ncbi.nlm.nih.gov/pubmed/19421388
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author Kosger, H. Huseyin
Ozturk, Mustafa
Sokmen, Atalay
Bulut, Eray
Ay, Sinan
author_facet Kosger, H. Huseyin
Ozturk, Mustafa
Sokmen, Atalay
Bulut, Eray
Ay, Sinan
author_sort Kosger, H. Huseyin
collection PubMed
description OBJECTIVES: The aim of this study was to investigate wound healing effects of Arnebia densiflora (Nordm.) Ledeb. root extracts on rat palatal mucosa. METHODS: A 10-mm full-thickness mucosal wounds were created on midline of rats’ palate by using scalpel. In the experimental groups, a ten percent extract of A. densiflora roots was topically applied once a day as ointment on the wounds. After wounding, tissue samples from palatal mucosa were harvested at 4, 7, 14 and 21 days and then evaluated histologically. RESULTS: It was observed that 10% A. densiflora root extract has progressive effects on wound healing in experimental groups. CONCLUSIONS: This study suggests that A. densiflora root extract could be developed as a therapeutic agent for wound healing.
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spelling pubmed-26760672009-05-06 Wound Healing Effects of Arnebia Densiflora Root Extracts on Rat Palatal Mucosa Kosger, H. Huseyin Ozturk, Mustafa Sokmen, Atalay Bulut, Eray Ay, Sinan Eur J Dent Articles OBJECTIVES: The aim of this study was to investigate wound healing effects of Arnebia densiflora (Nordm.) Ledeb. root extracts on rat palatal mucosa. METHODS: A 10-mm full-thickness mucosal wounds were created on midline of rats’ palate by using scalpel. In the experimental groups, a ten percent extract of A. densiflora roots was topically applied once a day as ointment on the wounds. After wounding, tissue samples from palatal mucosa were harvested at 4, 7, 14 and 21 days and then evaluated histologically. RESULTS: It was observed that 10% A. densiflora root extract has progressive effects on wound healing in experimental groups. CONCLUSIONS: This study suggests that A. densiflora root extract could be developed as a therapeutic agent for wound healing. Dental Investigations Society 2009-04 /pmc/articles/PMC2676067/ /pubmed/19421388 Text en Copyright 2009 European Journal of Dentistry. All rights reserved.
spellingShingle Articles
Kosger, H. Huseyin
Ozturk, Mustafa
Sokmen, Atalay
Bulut, Eray
Ay, Sinan
Wound Healing Effects of Arnebia Densiflora Root Extracts on Rat Palatal Mucosa
title Wound Healing Effects of Arnebia Densiflora Root Extracts on Rat Palatal Mucosa
title_full Wound Healing Effects of Arnebia Densiflora Root Extracts on Rat Palatal Mucosa
title_fullStr Wound Healing Effects of Arnebia Densiflora Root Extracts on Rat Palatal Mucosa
title_full_unstemmed Wound Healing Effects of Arnebia Densiflora Root Extracts on Rat Palatal Mucosa
title_short Wound Healing Effects of Arnebia Densiflora Root Extracts on Rat Palatal Mucosa
title_sort wound healing effects of arnebia densiflora root extracts on rat palatal mucosa
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676067/
https://www.ncbi.nlm.nih.gov/pubmed/19421388
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