A novel HIV-1 restriction factor that is biologically distinct from APOBEC3 cytidine deaminases in a human T cell line CEM.NKR

BACKGROUND: Isolation of novel retroviral restriction factors will open new avenues for anti-HIV/AIDS treatment. Although HIV-1 replication is restricted by APOBEC3G/APOBEC3F, TRIM5α, and CD317, none defend HIV-1 infection under natural conditions. Previously, we demonstrated a host factor from the...

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Detalles Bibliográficos
Autores principales: Zhou, Tao, Han, Yanxing, Dang, Ying, Wang, Xiaojun, Zheng, Yong-Hui
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676246/
https://www.ncbi.nlm.nih.gov/pubmed/19344514
http://dx.doi.org/10.1186/1742-4690-6-31

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