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Prediction of guide strand of microRNAs from its sequence and secondary structure

BACKGROUND: MicroRNAs (miRNAs) are produced by the sequential processing of a long hairpin RNA transcript by Drosha and Dicer, an RNase III enzymes, and form transitory small RNA duplexes. One strand of the duplex, which incorporates into RNA-induced silencing complex (RISC) and silences the gene ex...

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Detalles Bibliográficos
Autores principales: Ahmed, Firoz, Ansari, Hifzur Rahman, Raghava, Gajendra PS
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676257/
https://www.ncbi.nlm.nih.gov/pubmed/19358699
http://dx.doi.org/10.1186/1471-2105-10-105