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Prediction of guide strand of microRNAs from its sequence and secondary structure
BACKGROUND: MicroRNAs (miRNAs) are produced by the sequential processing of a long hairpin RNA transcript by Drosha and Dicer, an RNase III enzymes, and form transitory small RNA duplexes. One strand of the duplex, which incorporates into RNA-induced silencing complex (RISC) and silences the gene ex...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676257/ https://www.ncbi.nlm.nih.gov/pubmed/19358699 http://dx.doi.org/10.1186/1471-2105-10-105 |