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The Elg1 Clamp Loader Plays a Role in Sister Chromatid Cohesion

Mutations in the ELG1 gene of yeast lead to genomic instability, manifested in high levels of genetic recombination, chromosome loss, and gross chromosomal rearrangements. Elg1 shows similarity to the large subunit of the Replication Factor C clamp loader, and forms a RFC-like (RLC) complex in conju...

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Detalles Bibliográficos
Autores principales: Parnas, Oren, Zipin-Roitman, Adi, Mazor, Yuval, Liefshitz, Batia, Ben-Aroya, Shay, Kupiec, Martin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676507/
https://www.ncbi.nlm.nih.gov/pubmed/19430531
http://dx.doi.org/10.1371/journal.pone.0005497