HIF-1 Modulates Dietary Restriction-Mediated Lifespan Extension via IRE-1 in Caenorhabditis elegans

Dietary restriction (DR) extends lifespan in various species and also slows the onset of age-related diseases. Previous studies from flies and yeast have demonstrated that the target of rapamycin (TOR) pathway is essential for longevity phenotypes resulting from DR. TOR is a conserved protein kinase...

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Detalles Bibliográficos
Autores principales: Chen, Di, Thomas, Emma Lynn, Kapahi, Pankaj
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676694/
https://www.ncbi.nlm.nih.gov/pubmed/19461873
http://dx.doi.org/10.1371/journal.pgen.1000486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676694/
https://www.ncbi.nlm.nih.gov/pubmed/19461873
http://dx.doi.org/10.1371/journal.pgen.1000486

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