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Flux change in basophil membrane is not the main pathogenesis for hypersensitivity

The oxidation process is one of the most important natural processes. Oxidative change in hypersensitivity is believed to be an important process in the pathogenesis. However, the clear explanation on the transmembrane flux change of basophil and its correlation to hypersensitivity pathogenesis has...

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Detalles Bibliográficos
Autor principal: Wiwanitkit, Viroj
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676816/
https://www.ncbi.nlm.nih.gov/pubmed/18203432
Descripción
Sumario:The oxidation process is one of the most important natural processes. Oxidative change in hypersensitivity is believed to be an important process in the pathogenesis. However, the clear explanation on the transmembrane flux change of basophil and its correlation to hypersensitivity pathogenesis has never been reported. Here, the author determines the transmembrane oxidation flux in basophil. The simulation test to determine the oxidation flux change based on nanomedicine technique is used. Of interest, no change of flux can be detected. Therefore, this work can support the finding that the oxidation flux change is not an important part in the pathogenesis of basophil-related hypersensitivity.