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Clinical applications of perfluorocarbon nanoparticles for molecular imaging and targeted therapeutics
Molecular imaging is a novel tool that has allowed non-invasive diagnostic imaging to transition from gross anatomical description to identification of specific tissue epitopes and observation of biological processes at the cellular level. This technique has been confined to the field of nuclear ima...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676820/ https://www.ncbi.nlm.nih.gov/pubmed/18203420 |
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author | Tran, Trung D Caruthers, Shelton D Hughes, Michael Marsh, John N Cyrus, Tillmann Winter, Patrick M Neubauer, Anne M Wickline, Samuel A Lanza, Gregory M |
author_facet | Tran, Trung D Caruthers, Shelton D Hughes, Michael Marsh, John N Cyrus, Tillmann Winter, Patrick M Neubauer, Anne M Wickline, Samuel A Lanza, Gregory M |
author_sort | Tran, Trung D |
collection | PubMed |
description | Molecular imaging is a novel tool that has allowed non-invasive diagnostic imaging to transition from gross anatomical description to identification of specific tissue epitopes and observation of biological processes at the cellular level. This technique has been confined to the field of nuclear imaging; however, recent advances in nanotechnology have extended this research to include ultrasound (US) and magnetic resonance (MR) imaging. The exploitation of nanotechnology for MR and US molecular imaging has generated several candidate contrast agents. One multimodality platform, targeted perfluorocarbon (PFC) nanoparticles, is useful for noninvasive detection with US and MR, targeted drug delivery, and quantification. |
format | Text |
id | pubmed-2676820 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-26768202009-05-12 Clinical applications of perfluorocarbon nanoparticles for molecular imaging and targeted therapeutics Tran, Trung D Caruthers, Shelton D Hughes, Michael Marsh, John N Cyrus, Tillmann Winter, Patrick M Neubauer, Anne M Wickline, Samuel A Lanza, Gregory M Int J Nanomedicine Review Molecular imaging is a novel tool that has allowed non-invasive diagnostic imaging to transition from gross anatomical description to identification of specific tissue epitopes and observation of biological processes at the cellular level. This technique has been confined to the field of nuclear imaging; however, recent advances in nanotechnology have extended this research to include ultrasound (US) and magnetic resonance (MR) imaging. The exploitation of nanotechnology for MR and US molecular imaging has generated several candidate contrast agents. One multimodality platform, targeted perfluorocarbon (PFC) nanoparticles, is useful for noninvasive detection with US and MR, targeted drug delivery, and quantification. Dove Medical Press 2007-12 2007-12 /pmc/articles/PMC2676820/ /pubmed/18203420 Text en © 2007 Dove Medical Press Limited. All rights reserved |
spellingShingle | Review Tran, Trung D Caruthers, Shelton D Hughes, Michael Marsh, John N Cyrus, Tillmann Winter, Patrick M Neubauer, Anne M Wickline, Samuel A Lanza, Gregory M Clinical applications of perfluorocarbon nanoparticles for molecular imaging and targeted therapeutics |
title | Clinical applications of perfluorocarbon nanoparticles for molecular imaging and targeted therapeutics |
title_full | Clinical applications of perfluorocarbon nanoparticles for molecular imaging and targeted therapeutics |
title_fullStr | Clinical applications of perfluorocarbon nanoparticles for molecular imaging and targeted therapeutics |
title_full_unstemmed | Clinical applications of perfluorocarbon nanoparticles for molecular imaging and targeted therapeutics |
title_short | Clinical applications of perfluorocarbon nanoparticles for molecular imaging and targeted therapeutics |
title_sort | clinical applications of perfluorocarbon nanoparticles for molecular imaging and targeted therapeutics |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676820/ https://www.ncbi.nlm.nih.gov/pubmed/18203420 |
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