Bioavailability of Orally Administered rhGM-CSF: A Single-Dose, Randomized, Open-Label, Two-Period Crossover Trial

BACKGROUND: Recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) is usually administered by injection, and its oral administration in a clinical setting has been not yet reported. Here we demonstrate the bioavailability of orally administered rhGM-CSF in healthy volunteers....

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Detalles Bibliográficos
Autores principales: Zhang, Wenping, Lv, Zhengbing, Nie, Zuoming, Chen, Guogang, Chen, Jian, Sheng, Qing, Yu, Wei, Jin, Yongfeng, Wu, Xiangfu, Zhang, Yaozhou
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677157/
https://www.ncbi.nlm.nih.gov/pubmed/19434235
http://dx.doi.org/10.1371/journal.pone.0005353

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