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Artefacts and biases affecting the evaluation of scoring functions on decoy sets for protein structure prediction

Motivation: Decoy datasets, consisting of a solved protein structure and numerous alternative native-like structures, are in common use for the evaluation of scoring functions in protein structure prediction. Several pitfalls with the use of these datasets have been identified in the literature, as...

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Detalles Bibliográficos
Autores principales: Handl, Julia, Knowles, Joshua, Lovell, Simon C.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677743/
https://www.ncbi.nlm.nih.gov/pubmed/19297350
http://dx.doi.org/10.1093/bioinformatics/btp150