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Analysis of Combinatorial cis-Regulation in Synthetic and Genomic Promoters
Transcription factor binding sites (TFBS) are being discovered at a rapid pace1, 2. We must now begin to turn our attention towards understanding how these sites work in combination to influence gene expression. Quantitative models that accurately predict gene expression from promoter sequence3-5 wi...
Autores principales: | Gertz, Jason, Siggia, Eric D., Cohen, Barak A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677908/ https://www.ncbi.nlm.nih.gov/pubmed/19029883 http://dx.doi.org/10.1038/nature07521 |
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