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Cetuximab in combination with irinotecan/5-fluorouracil/folinic acid (FOLFIRI) in the initial treatment of metastatic colorectal cancer: a multicentre two-part phase I/II study
BACKGROUND: This study was designed to investigate the efficacy and safety of the epidermal growth factor receptor (EGFR) inhibitor cetuximab combined with irinotecan, folinic acid (FA) and two different doses of infusional 5-fluorouracil (5-FU) in the first-line treatment of EGFR-detectable metasta...
Autores principales: | Raoul, Jean-Luc, Van Laethem, Jean-Luc, Peeters, Marc, Brezault, Catherine, Husseini, Fares, Cals, Laurent, Nippgen, Johannes, Loos, Anja-Helena, Rougier, Philippe |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678147/ https://www.ncbi.nlm.nih.gov/pubmed/19366444 http://dx.doi.org/10.1186/1471-2407-9-112 |
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