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Mutation of a Single Residue Renders Human Tetherin Resistant to HIV-1 Vpu-Mediated Depletion

The recently identified restriction factor tetherin/BST-2/CD317 is an interferon-inducible trans-membrane protein that restricts HIV-1 particle release in the absence of the HIV-1 countermeasure viral protein U (Vpu). It is known that Tantalus monkey CV1 cells can be rendered non-permissive to HIV-1...

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Detalles Bibliográficos
Autores principales:	Gupta, Ravindra K., Hué, Stéphane, Schaller, Torsten, Verschoor, Ernst, Pillay, Deenan, Towers, Greg J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678251/ https://www.ncbi.nlm.nih.gov/pubmed/19461879 http://dx.doi.org/10.1371/journal.ppat.1000443

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