Cargando…

Dominant Negative Mutants of Bacillus thuringiensis Cry1Ab Toxin Function as Anti-Toxins: Demonstration of the Role of Oligomerization in Toxicity

BACKGROUND: Bacillus thuringiensis Cry toxins, that are used worldwide in insect control, kill insects by a mechanism that depends on their ability to form oligomeric pores that insert into the insect-midgut cells. These toxins are being used worldwide in transgenic plants or spray to control insect...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rodríguez-Almazán, Claudia, Zavala, Luis Enrique, Muñoz-Garay, Carlos, Jiménez-Juárez, Nuria, Pacheco, Sabino, Masson, Luke, Soberón, Mario, Bravo, Alejandra
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678262/ https://www.ncbi.nlm.nih.gov/pubmed/19440244 http://dx.doi.org/10.1371/journal.pone.0005545

Ejemplares similares

Correction: Dominant Negative Mutants of Bacillus thuringiensis Cry1Ab Toxin Function as Anti-Toxins: Demonstration of the Role of Oligomerization in Toxicity
por: Rodríguez-Almazán, Claudia, et al.
Publicado: (2013)

Dominant Negative Phenotype of Bacillus thuringiensis Cry1Ab, Cry11Aa and Cry4Ba Mutants Suggest Hetero-Oligomer Formation among Different Cry Toxins
por: Carmona, Daniela, et al.
Publicado: (2011)

Evolution of Bacillus thuringiensis Cry toxins insecticidal activity
por: Bravo, Alejandra, et al.
Publicado: (2013)

Rearrangement of N-Terminal α-Helices of Bacillus thuringiensis Cry1Ab Toxin Essential for Oligomer Assembly and Toxicity
por: Pacheco, Sabino, et al.
Publicado: (2020)

ABCC2 is associated with Bacillus thuringiensis Cry1Ac toxin oligomerization and membrane insertion in diamondback moth
por: Ocelotl, Josue, et al.
Publicado: (2017)

The Cadherin Protein Is Not Involved in Susceptibility to Bacillus thuringiensis Cry1Ab or Cry1Fa Toxins in Spodoptera frugiperda
por: Zhang, Jianfeng, et al.
Publicado: (2020)

Improvement and efficient display of Bacillus thuringiensis toxins on M13 phages and ribosomes
por: Pacheco, Sabino, et al.
Publicado: (2015)

Helix α-3 inter-molecular salt bridges and conformational changes are essential for toxicity of Bacillus thuringiensis 3D-Cry toxin family
por: Pacheco, Sabino, et al.
Publicado: (2018)

Bacillus thuringiensis Cry1A toxins are versatile proteins with multiple modes of action: two distinct pre-pores are involved in toxicity
por: Gómez, Isabel, et al.
Publicado: (2014)

Characterization of Two Novel Bacillus thuringiensis Cry8 Toxins Reveal Differential Specificity of Protoxins or Activated Toxins against Chrysomeloidea Coleopteran Superfamily
por: Shu, Changlong, et al.
Publicado: (2020)

Efficacy of Genetically Modified Bt Toxins Alone and in Combinations Against Pink Bollworm Resistant to Cry1Ac and Cry2Ab
por: Tabashnik, Bruce E., et al.
Publicado: (2013)

In vivo nanoscale analysis of the dynamic synergistic interaction of Bacillus thuringiensis Cry11Aa and Cyt1Aa toxins in Aedes aegypti
por: López-Molina, Samira, et al.
Publicado: (2021)

Composition of the Putative Prepore Complex of Bacillus thuringiensis Cry1Ab Toxin
por: Nair, Manoj S., et al.
Publicado: (2015)

Characterization of the Cry1Ah resistance in Asian corn Borer and its cross-resistance to other Bacillus thuringiensis toxins
por: Shabbir, Muhammad Zeeshan, et al.
Publicado: (2018)

Role of UPR Pathway in Defense Response of Aedes aegypti against Cry11Aa Toxin from Bacillus thuringiensis
por: Bedoya-Pérez, Leidy P., et al.
Publicado: (2013)

Transcriptional cellular responses in midgut tissue of Aedes aegypti larvae following intoxication with Cry11Aa toxin from Bacillus thuringiensis
por: Canton, Pablo Emiliano, et al.
Publicado: (2015)

Engineering Bacillus thuringiensis Cyt1Aa toxin specificity from dipteran to lepidopteran toxicity
por: Torres-Quintero, Mary-Carmen, et al.
Publicado: (2018)

The Cadherin Cry1Ac Binding-Region is Necessary for the Cooperative Effect with ABCC2 Transporter Enhancing Insecticidal Activity of Bacillus thuringiensis Cry1Ac Toxin
por: Ma, Yuemin, et al.
Publicado: (2019)

Resistance to Bacillus thuringiensis toxin Cry2Ab and survival on single‐toxin and pyramided cotton in cotton bollworm from China
por: Liu, Laipan, et al.
Publicado: (2016)

Genetic Basis of Cry1F-Resistance in a Laboratory Selected Asian Corn Borer Strain and Its Cross-Resistance to Other Bacillus thuringiensis Toxins
por: Wang, Yueqin, et al.
Publicado: (2016)

Insect chaperones Hsp70 and Hsp90 cooperatively enhance toxicity of Bacillus thuringiensis Cry1A toxins and counteract insect resistance
por: García-Gomez, Blanca Ines, et al.
Publicado: (2023)

Key residues of Bacillus thuringiensis Cry2Ab for oligomerization and pore-formation activity
por: Pan, Zhi-Zhen, et al.
Publicado: (2021)

Comparative Proteomic Analysis of Aedes aegypti Larval Midgut after Intoxication with Cry11Aa Toxin from Bacillus thuringiensis
por: Cancino-Rodezno, Angeles, et al.
Publicado: (2012)

Structural Insights into Bacillus thuringiensis Cry, Cyt and Parasporin Toxins
por: Xu, Chengchen, et al.
Publicado: (2014)

Interaction of Fluorescently Labeled Cadherin G Protein-coupled Receptor with the Cry1Ab Toxin of Bacillus thuringiensis
por: Liu, Li, et al.
Publicado: (2018)

Resistance of Trichoplusia ni to Bacillus thuringiensis Toxin Cry1Ac Is Independent of Alteration of the Cadherin-Like Receptor for Cry Toxins
por: Zhang, Xin, et al.
Publicado: (2012)

Effect of crop plants on fitness costs associated with resistance to Bacillus thuringiensis toxins Cry1Ac and Cry2Ab in cabbage loopers
por: Wang, Ran, et al.
Publicado: (2016)

Molecular Approaches to Improve the Insecticidal Activity of Bacillus thuringiensis Cry Toxins
por: Lucena, Wagner A., et al.
Publicado: (2014)

Molecular and Kinetic Models for Pore Formation of Bacillus thuringiensis Cry Toxin
por: Endo, Haruka
Publicado: (2022)

“The Defined Toxin-binding Region of the Cadherin G-protein Coupled Receptor, BT-R(1), for the Active Cry1Ab Toxin of Bacillus thuringiensis”
por: Liu, Li, et al.
Publicado: (2018)

A novel recombinant baculovirus overexpressing a Bacillus thuringiensis Cry1Ab toxin enhances insecticidal activity
por: El-Menofy, Wael, et al.
Publicado: (2014)

Insect Resistance to Bacillus thuringiensis Toxin Cry2Ab Is Conferred by Mutations in an ABC Transporter Subfamily A Protein
por: Tay, Wee Tek, et al.
Publicado: (2015)

In Silico Modeling and Functional Interpretations of Cry1Ab15 Toxin from Bacillus thuringiensis BtB-Hm-16
por: Kashyap, Sudhanshu
Publicado: (2013)

Identification and Characterization of Hyphantria cunea Aminopeptidase N as a Binding Protein of Bacillus thuringiensis Cry1Ab35 Toxin
por: Zhang, Yakun, et al.
Publicado: (2017)

Insecticidal Effects of Hemocoelic Delivery of Bacillus thuringiensis Cry Toxins in Achaea janata Larvae
por: Ningshen, Thuirei J., et al.
Publicado: (2017)

Different Effects of Bacillus thuringiensis Toxin Cry1Ab on Midgut Cell Transmembrane Potential of Mythimna separata and Agrotis ipsilon Larvae
por: Wang, Yingying, et al.
Publicado: (2015)

Synergistic activity between Bacillus thuringiensis Cry6Aa and Cry55Aa toxins against Meloidogyne incognita
por: Peng, Donghai, et al.
Publicado: (2011)

Binding and Oligomerization of Modified and Native Bt Toxins in Resistant and Susceptible Pink Bollworm
por: Ocelotl, Josue, et al.
Publicado: (2015)

Addendum: Bedoya-Pérez, L.P. et al. Role of UPR Pathway in Defense Response of Aedes aegypti against Cry11Aa Toxin from Bacillus thuringiensis. Int. J. Mol. Sci. 2013, 14, 8467–8478
por: Bedoya-Pérez, Leidy P., et al.
Publicado: (2016)

An ABC Transporter Mutation Is Correlated with Insect Resistance to Bacillus thuringiensis Cry1Ac Toxin
por: Gahan, Linda J., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_8vnoi9ck7kt2n6v2iahv3fl2dd