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Deaminase-Independent Inhibition of Parvoviruses by the APOBEC3A Cytidine Deaminase
The APOBEC3 proteins form a multigene family of cytidine deaminases with inhibitory activity against viruses and retrotransposons. In contrast to APOBEC3G (A3G), APOBEC3A (A3A) has no effect on lentiviruses but dramatically inhibits replication of the parvovirus adeno-associated virus (AAV). To stud...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678267/ https://www.ncbi.nlm.nih.gov/pubmed/19461882 http://dx.doi.org/10.1371/journal.ppat.1000439 |