Deaminase-Independent Inhibition of Parvoviruses by the APOBEC3A Cytidine Deaminase

The APOBEC3 proteins form a multigene family of cytidine deaminases with inhibitory activity against viruses and retrotransposons. In contrast to APOBEC3G (A3G), APOBEC3A (A3A) has no effect on lentiviruses but dramatically inhibits replication of the parvovirus adeno-associated virus (AAV). To stud...

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Detalles Bibliográficos
Autores principales: Narvaiza, Iñigo, Linfesty, Daniel C., Greener, Benjamin N., Hakata, Yoshiyuki, Pintel, David J., Logue, Eric, Landau, Nathaniel R., Weitzman, Matthew D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678267/
https://www.ncbi.nlm.nih.gov/pubmed/19461882
http://dx.doi.org/10.1371/journal.ppat.1000439

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