Modulation of the anti-tumor immune response by complement

The involvement of complement activation products in promoting tumor growth has not yet been recognized. Here we show that generation of complement C5a in the tumor microenvironment enhanced tumor growth by suppressing the anti-tumor CD8(+) T cell-mediated response. This suppression was associated w...

Descripción completa

Detalles Bibliográficos
Autores principales: Markiewski, Maciej M., DeAngelis, Robert A., Benencia, Fabian, Ricklin-Lichtsteiner, Salome K., Koutoulaki, Anna, Gerard, Craig, Coukos, George, Lambris, John D.
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678913/
https://www.ncbi.nlm.nih.gov/pubmed/18820683
http://dx.doi.org/10.1038/ni.1655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678913/
https://www.ncbi.nlm.nih.gov/pubmed/18820683
http://dx.doi.org/10.1038/ni.1655

Ejemplares similares