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Modulation of the anti-tumor immune response by complement
The involvement of complement activation products in promoting tumor growth has not yet been recognized. Here we show that generation of complement C5a in the tumor microenvironment enhanced tumor growth by suppressing the anti-tumor CD8(+) T cell-mediated response. This suppression was associated w...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678913/ https://www.ncbi.nlm.nih.gov/pubmed/18820683 http://dx.doi.org/10.1038/ni.1655 |