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Increased nucleotide polymorphic changes in the 5′-untranslated region of δ-catenin (CTNND2) gene in prostate cancer

Cancer pathogenesis involves multiple genetic and epigenetic alterations, which result in oncogenic changes in gene expression. δ-Catenin (CTNND2) is overexpressed in cancer although the mechanisms of its upregulation are highly variable. Here we report that in prostate cancer the methylation of CpG...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Chen, Yan-Hua, Hong, Heng, Zeng, Yan, Zhang, Jiao, Lu, Jian-Ping, Jeansonne, Beverly, Lu, Qun
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678952/
https://www.ncbi.nlm.nih.gov/pubmed/18978817
http://dx.doi.org/10.1038/onc.2008.399