A modified and automated version of the 'Fluorimetric Detection of Alkaline DNA Unwinding' method to quantify formation and repair of DNA strand breaks

BACKGROUND: Formation and repair of DNA single-strand breaks are important parameters in the assessment of DNA damage and repair occurring in live cells. The 'Fluorimetric Detection of Alkaline DNA Unwinding (FADU)' method [Birnboim HC, Jevcak JJ. Cancer Res (1981) 41:1889–1892] is a sensi...

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Detalles Bibliográficos
Autores principales: Moreno-Villanueva, María, Pfeiffer, Ragen, Sindlinger, Thilo, Leake, Alan, Müller, Marcus, Kirkwood, Thomas BL, Bürkle, Alexander
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679009/
https://www.ncbi.nlm.nih.gov/pubmed/19389244
http://dx.doi.org/10.1186/1472-6750-9-39

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