Quantitation of DNA methylation by melt curve analysis

BACKGROUND: Methylation of DNA is a common mechanism for silencing genes, and aberrant methylation is increasingly being implicated in many diseases such as cancer. There is a need for robust, inexpensive methods to quantitate methylation across a region containing a number of CpGs. We describe and...

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Detalles Bibliográficos
Autores principales: Smith, Eric, Jones, Michael E, Drew, Paul A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679043/
https://www.ncbi.nlm.nih.gov/pubmed/19393074
http://dx.doi.org/10.1186/1471-2407-9-123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679043/
https://www.ncbi.nlm.nih.gov/pubmed/19393074
http://dx.doi.org/10.1186/1471-2407-9-123

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