Stem Cell Factor SALL4 Represses the Transcriptions of PTEN and SALL1 through an Epigenetic Repressor Complex

BACKGROUND: The embryonic stem cell (ESC) factor, SALL4, plays an essential role in both development and leukemogenesis. It is a unique gene that is involved in self-renewal in ESC and leukemic stem cell (LSC). METHODOLOGY/PRINCIPAL FINDINGS: To understand the mechanism(s) of SALL4 function(s), we s...

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Detalles Bibliográficos
Autores principales: Lu, Jiayun, Jeong, Hawon, Kong, Nikki, Yang, Youyang, Carroll, John, Luo, Hongbo R., Silberstein, Leslie E., YupoMa, Chai, Li
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679146/
https://www.ncbi.nlm.nih.gov/pubmed/19440552
http://dx.doi.org/10.1371/journal.pone.0005577

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