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Manipulation of Cell:Cell Contacts and Mesoderm Suppressing Activity Direct Lineage Choice from Pluripotent Primitive Ectoderm-Like Cells in Culture
In the mammal, the pluripotent cells of embryo differentiate and commit to either the mesoderm/endoderm lineages or the ectoderm lineage during gastrulation. In culture, the ability to direct lineage choice from pluripotent cells into the mesoderm/endoderm or ectoderm lineages will enable the develo...
Autores principales: | Hughes, James N., Washington, Jennifer M., Zheng, Zhiqiang, Lau, Xiuwen K., Yap, Charlotte, Rathjen, Peter D., Rathjen, Joy |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679147/ https://www.ncbi.nlm.nih.gov/pubmed/19440553 http://dx.doi.org/10.1371/journal.pone.0005579 |
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